SCHEMBL7632026

SCHEMBL7632026

C=C[Si](CC)(CC)c1ccc(C=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
ALDH1A3 P47895 3/20 0.42
ALDH3A1 P30838 2/20 0.42
CYP2A6 P11509 4/20 0.40
TYR P14679 1/20 0.36
CYP2A13 Q16696 1/20 0.36
HSD17B10 Q99714 1/20 0.35
ALDH5A1 P51649 1/20 0.35
ABAT P80404 1/20 0.35
BRD4 O60885 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6114590 0.85 ESR1 (0.36)
SCHEMBL10626368 0.84 ALDH1A1 (0.46) ALDH1A1
SCHEMBL7637239 0.81 ALDH1A1 (0.42) ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR
SCHEMBL7633313 0.79 ALDH1A1 (0.39) ALDH1A1ALDH1A3CYP2A6BRD4
SCHEMBL7632023 0.76
SCHEMBL3422339 0.75 ALDH1A1 (0.33) ALDH1A1MAPTHPGDKDM4E
SCHEMBL10490642 0.74 ALDH1A1 (0.47) ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR
SCHEMBL7635468 0.74 BRD4 (0.46) ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR
SCHEMBL7630321 0.74 NR1H2 (0.47) ALDH1A1ALDH1A3ALDH3A1CYP2A6TYR
SCHEMBL6114536 0.69 TP53 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed