Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625394 | 0.87 | MEN1 (0.42) | NPC1MAPTRAB9AKMT2ACYP1A2 | |
| SCHEMBL7633002 | 0.85 | MAPT (0.44) | NPC1MAPTRAB9AKMT2AESR1 | |
| SCHEMBL7630715 | 0.85 | TDP1 (0.49) | MAPTKMT2AGAAKDM4EMEN1 | |
| SCHEMBL7637310 | 0.85 | ESR1 (0.50) | NPC1RAB9AKMT2AESR1MAPK1 | |
| SCHEMBL7634492 | 0.85 | TDP1 (0.44) | NPC1MAPTRAB9AGAAALDH1A1 | |
| SCHEMBL7625629 | 0.84 | KMT2A (0.47) | NPC1MAPTRAB9AKMT2AGAA | |
| SCHEMBL7629617 | 0.83 | KMT2A (0.41) | NPC1MAPTRAB9AKMT2ACYP1A2 | |
| SCHEMBL7627887 | 0.82 | KMT2A (0.50) | NPC1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL7634944 | 0.82 | RAB9A (0.46) | NPC1MAPTRAB9AKMT2AKDM4E | |
| SCHEMBL7632992 | 0.82 | NPC1 (0.41) | NPC1MAPTADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |