Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639801 | 0.97 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7642058 | 0.95 | ITGB3 (0.47) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL7634297 | 0.95 | ITGB3 (0.48) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7632999 | 0.94 | ITGB3 (0.54) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7640382 | 0.93 | ITGB3 (0.46) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL6600970 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7638997 | 0.92 | ITGB3 (0.49) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7640069 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1GRM2F10 | |
| SCHEMBL7642004 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BSIGMAR1F10PRSS1 | |
| Gantofiban SCHEMBL7633249 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BSIGMAR1GRM2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |