Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639803 | 0.94 | ITGB3 (0.41) | ITGB3ITGA2BSIGMAR1CASRLMNA | |
| SCHEMBL6600556 | 0.94 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1CASRPRSS1 | |
| SCHEMBL7637336 | 0.93 | ITGB3 (0.43) | ITGB3ITGA2BSIGMAR1CASRLMNA | |
| SCHEMBL7639408 | 0.91 | ITGB3 (0.37) | ITGB3ITGA2BSIGMAR1CASRPRSS1 | |
| SCHEMBL7640448 | 0.91 | ITGB3 (0.38) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL7631939 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BSIGMAR1GRM2 | |
| SCHEMBL7641756 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BSIGMAR1HTR2BGRM2 | |
| SCHEMBL7633585 | 0.87 | ITGB3 (0.38) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 | |
| SCHEMBL6602794 | 0.87 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1CASRPRSS1 | |
| SCHEMBL7636700 | 0.87 | ITGB3 (0.40) | ITGB3ITGA2BSIGMAR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |