Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.33 |
| ▸ | F10 | P00742 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633348 | 0.93 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7304816 | 0.92 | ITGB3 (0.40) | ITGB3ITGA2BPOLBSIGMAR1CYP3A4 | |
| SCHEMBL7304473 | 0.89 | ITGB3 (0.47) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7306839 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BPOLBSIGMAR1CYP3A4 | |
| SCHEMBL7671038 | 0.87 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7314935 | 0.87 | ITGB3 (0.42) | ITGB3ITGA2BSIGMAR1 | |
| SCHEMBL7318763 | 0.84 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7314740 | 0.84 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7639812 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7304501 | 0.82 | ITGB3 (0.45) | ITGB3ITGA2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |