Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638388 | 0.93 | NPC1 (0.66) | NPC1KMT2AMEN1HIF1AMAPT | |
| SCHEMBL7631355 | 0.88 | NPC1 (0.71) | NPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL29483366 | 0.88 | NPC1 (0.71) | NPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL30444952 | 0.83 | DRD2 (0.61) | KMT2AMEN1HIF1AMAPTKDM4E | |
| SCHEMBL5598745 | 0.83 | DRD2 (0.61) | KMT2AMEN1HIF1AMAPTKDM4E | |
| SCHEMBL7645232 | 0.82 | KDM4E (0.58) | KMT2AMEN1HIF1AMAPTKDM4E | |
| SCHEMBL1549099 | 0.82 | NPC1 (0.72) | NPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28625679 | 0.81 | KMT2A (0.53) | KMT2AMEN1HIF1AMAPTKDM4E | |
| Water SCHEMBL27563973 | 0.81 | DRD2 (0.59) | KMT2AMEN1HIF1AMAPTKDM4E | |
| SCHEMBL28961946 | 0.81 | MAPT (0.53) | NPC1KMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448304-B1 | POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS | HOYA CORPORATION (JP) | 2002-09-10 | — | — | US | disclosed |