Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.58 |
| ▸ | ITGAL | P20701 | 3/20 | 0.58 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | PRKCG | P05129 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | ROS1 | P08922 | 1/20 | 0.54 |
| ▸ | KIT | P10721 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139179 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| SCHEMBL6139174 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| SCHEMBL15854225 | 0.83 | ALDH1A1 (0.63) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| Hydrochloric Acid SCHEMBL6139394 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| Hydrochloric Acid SCHEMBL6139391 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| SCHEMBL6109371 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| SCHEMBL6109373 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| Hydrochloric Acid SCHEMBL17219646 | 0.83 | ALDH1A1 (0.62) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| Hydrochloric Acid SCHEMBL17219644 | 0.83 | ALDH1A1 (0.62) | ALDH1A1ITGB2ICAM1ITGALPLK4 | |
| SCHEMBL6094971 | 0.81 | ALDH1A1 (0.60) | ALDH1A1ITGB2ICAM1ITGALPLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263712-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002074731-A1 | 3-(2,5-DIAMINOPHENYL)-ACRYLAMIDE DERIVATIVES AND COLOURING AGENTS CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-26 | — | — | WO | disclosed |