SCHEMBL7633920

SCHEMBL7633920

CN/C(=N\C#N)NCc1cnc(Cl)s1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.31
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633927 1.00 L3MBTL1 (0.33) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL13240168 0.85 KMT2A (0.36) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL14947512 0.82 KMT2A (0.36) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL12842341 0.81 KMT2A (0.35) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL18400751 0.81 KMT2A (0.35) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL13359523 0.81 L3MBTL1 (0.34) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL7764246 0.80 L3MBTL1 (0.34) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL7764248 0.80 L3MBTL1 (0.34) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL10062582 0.79 L3MBTL1 (0.39) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL14606375 0.77 L3MBTL1 (0.32) L3MBTL1KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140350-A APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US claimed
US-6403058-B1 CONTROLLING TERMITES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-11 US disclosed
US-6391327-B1 SYNERGISTIC PESTICIDAL COMPOSITION COMPRISING PRALLETHRIN AND NEONICOTINOID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-21 US disclosed
US-6284782-B1 INSECTICIDES; SYNERGISTIC MIXTURES SUMITOMO CHEMICAL CO., LTD. (JP) 2001-09-04 US disclosed
US-6255340-B1 SYNERGISTIC MIXTURE OF PRALLETHRIN AND A NEONICOTINOID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-03 US disclosed
US-6201017-B1 TOPICALLY APPLYING TO ANIMAL A LIQUID MIXTURE COMPRISING 1-(TETRAHYDRUFURAN-3-YL)METHYL-3-METHYL-2-NITROGUANIDINE, A GLYCOL OR ITS MONOALKYL ETHER AND A SOLVENT TO CONTROL FLEAS, LICE, TICKS SUMITOMO CHEMICAL CO., LTD. (JP) 2001-03-13 US disclosed
US-6140350-A APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed
EP-0976328-A2 Ectoparasite controlling agent for animals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
EP-0966961-A1 Method for controlling ectoparasites SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-29 EP disclosed