SCHEMBL7633965

SCHEMBL7633965

CCCCCC1CCN(C)C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
CHRNB2 P17787 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
GBA1 P04062 1/20 0.35
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
S1PR5 Q9H228 2/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALOX5 P09917 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
CHRM3 P20309 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8333332 0.98 CYP1A2 (0.41) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL31026188 0.98 CYP1A2 (0.41) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL21596445 0.98 CYP1A2 (0.41) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL3792450 0.98 CYP1A2 (0.41) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL4486955 0.98 CYP1A2 (0.41) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL8085940 0.94 ALDH1A1 (0.36) CYP1A2GBA1CHRM2CHRM4CHRM5
SCHEMBL28905056 0.88 S1PR1 (0.40) CYP1A2CHRNB2CHRNA7CHRNA4GBA1
SCHEMBL18068300 0.86 AR (0.31)
SCHEMBL18068301 0.86 AR (0.31)
SCHEMBL11697415 0.86 AR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973710-B1 OMEGA-AMINO ACID DERIVATIVES, PROCESSES OF THEIR PREPARATION AND THEIR USE BOCHEMIE S R O (CZ) 2002-02-06 EP disclosed
US-6187938-B1 TRANSDERMAL PENETRATION ENHANCERS BOCHEMIE, S.R.O. (CZ) 2001-02-13 US disclosed
EP-0973710-A2 OMEGA-AMINO ACID DERIVATIVES, PROCESSES OF THEIR PREPARATION AND THEIR USE Bochemie S.R.O. (CZ) 2000-01-26 EP disclosed
WO-1998045233-A2 OMEGA-AMINO ACID DERIVATIVES, PROCESSES OF THEIR PREPARATION AND THEIR USE BOCHEMIE S.R.O. (CZ) 1998-10-15 WO disclosed