Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.51 |
| ▸ | F10 | P00742 | 13/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313697 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7639790 | 0.90 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7637832 | 0.89 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7637817 | 0.89 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7633578 | 0.88 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7638635 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL6602189 | 0.87 | GRM2 (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7639213 | 0.87 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7634270 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7639427 | 0.87 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |