SCHEMBL7634751

SCHEMBL7634751

CC(C)(C)c1ncn(CC(O)CCc2ccc(Cl)cc2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
CYP3A4 P08684 2/20 0.38
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
CNR2 P34972 2/20 0.34
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NR1I2 O75469 1/20 0.32
ESR1 P03372 1/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
ADORA3 P0DMS8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9059557 0.82 SLC6A2 (0.40) ALDH1A1CNR2SLC6A3
SCHEMBL5466563 0.71 ALDH1A1 (0.44) ALDH1A1CYP3A4KMT2AMEN1CNR2
SCHEMBL12045404 0.68 MEN1 (0.49) ALDH1A1KMT2AMEN1LMNAKCNH2
SCHEMBL409343 0.68 ALDH1A1 (0.59) ALDH1A1CYP3A4LMNATP53CYP1A2
SCHEMBL17077999 0.68 KMT2A (0.38) ALDH1A1CYP3A4KMT2AMEN1TP53
Hydrochloric Acid SCHEMBL9996066 0.68 MEN1 (0.48) ALDH1A1KMT2AMEN1LMNA
SCHEMBL14135335 0.67 TAAR1 (0.44) ALDH1A1KMT2AMEN1CYP1A2CYP2D6
Hydrochloric Acid SCHEMBL408521 0.67 ALDH1A1 (0.58) ALDH1A1CYP3A4LMNATP53CYP1A2
SCHEMBL8161937 0.66 TAAR1 (0.42) ALDH1A1KMT2AMEN1LMNACYP1A2
SCHEMBL8439467 0.66 ALDH1A1 (0.36) ALDH1A1CYP3A4KMT2AMEN1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6464764-B1 Protective agents for wood LONZA AG (CH) 2002-10-15 US disclosed