Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863667 | 0.76 | CNR2 (0.47) | KMT2ATOP2ATOP2BCNR2ALDH1A1 | |
| SCHEMBL13761459 | 0.75 | ADRB2 (0.45) | KMT2ACNR2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13761466 | 0.75 | ADRB2 (0.45) | KMT2ACNR2ALDH1A1LMNAMEN1 | |
| SCHEMBL7048885 | 0.73 | CA1 (0.41) | TOP2ATOP2BSMN1; SMN2LMNACYP2D6 | |
| SCHEMBL1327564 | 0.73 | CNR2 (0.40) | KMT2ACNR2PKMSMN1; SMN2LMNA | |
| Bicarbonate SCHEMBL10932098 | 0.72 | CNR2 (0.43) | KMT2APOLBCNR2ALDH1A1LMNA | |
| SCHEMBL12185663 | 0.72 | KCNH2 (0.47) | KMT2APOLBCNR2ALDH1A1LMNA | |
| SCHEMBL477540 | 0.71 | IDO1 (0.55) | KMT2APOLBCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30476555 | 0.71 | IDO1 (0.55) | KMT2APOLBCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL30273872 | 0.71 | IDO1 (0.55) | KMT2APOLBCNR2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224195-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027128-A1 | C-ARYL GLUCOSIDE SGLT2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |