Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.54 |
| ▸ | APP | P05067 | 4/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449840 | 0.86 | MAPT (0.76) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL4449836 | 0.86 | MAPT (0.76) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL25191799 | 0.82 | ABCG2 (0.77) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL25195734 | 0.79 | CYP3A4 (0.62) | MAPTMEN1MAPK1KMT2ACHRNA7 | |
| SCHEMBL30383778 | 0.78 | MAOB (0.66) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL25210434 | 0.78 | MAOB (0.66) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL7637445 | 0.78 | MAOB (0.66) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL4456570 | 0.77 | ABCG2 (0.76) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL4456573 | 0.77 | ABCG2 (0.76) | MAPTMEN1MAPK1KMT2ANPC1 | |
| SCHEMBL25191038 | 0.75 | GUSB (0.55) | MAPTMEN1MAPK1KMT2AABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423740-B1 | ANTICARCINOGENIC AGENTS | INDENA S.P.A. (IT) | 2002-07-23 | — | — | US | claimed |
| US-6423740-B1 | ANTICARCINOGENIC AGENTS | INDENA S.P.A. (IT) | 2002-07-23 | — | — | US | disclosed |