Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21639308 | 0.87 | PTGDR2 (0.44) | PTGDR2HPGDERN1TSHRPOLB | |
| SCHEMBL30457873 | 0.87 | PTGDR2 (0.44) | PTGDR2HPGDERN1TSHRPOLB | |
| SCHEMBL4936956 | 0.84 | HPGD (0.67) | PTGDR2HPGDERN1TSHRPOLB | |
| SCHEMBL2422003 | 0.81 | TSHR (0.48) | PTGDR2HPGDERN1TSHRTDP1 | |
| SCHEMBL21877484 | 0.81 | ALDH1A1 (0.47) | PTGDR2HPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28342817 | 0.81 | ALDH1A1 (0.44) | PTGDR2HPGDERN1TSHRL3MBTL1 | |
| SCHEMBL22636353 | 0.79 | TP53 (0.40) | PTGDR2HPGDTSHRPOLBCTDSP1 | |
| SCHEMBL8314602 | 0.78 | KDM4E (0.51) | ERN1POLBALDH1A1RAB9AKMT2A | |
| SCHEMBL28340278 | 0.78 | ALDH1A1 (0.38) | PTGDR2HPGDALDH1A1RAB9AKMT2A | |
| SCHEMBL155442 | 0.78 | HPGD (0.64) | PTGDR2HPGDERN1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | claimed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110642818-B | Method for preparing benzofuran-2-carboxamide compound | 云南师范大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-110642818-A | Method for preparing benzofuran-2-formamide compound | 云南师范大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |