SCHEMBL7635129

SCHEMBL7635129

C=C[Si](C)(C)c1ccc(C(=O)OOC(=C)OOC(=O)c2ccc([Si](C)(C)C=C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
F2 P00734 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.34
SNCA P37840 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CA12 O43570 2/20 0.32
CA7 P43166 2/20 0.32
CA9 Q16790 2/20 0.32
CA14 Q9ULX7 2/20 0.32
TDP1 Q9NUW8 2/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636200 0.87 LMNA (0.37) F2LMNAHPGDSNCACA1
SCHEMBL7634520 0.87 NR1H2 (0.41) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7631139 0.85 NR1H2 (0.42) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7631205 0.83 NR1H2 (0.39) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7636230 0.83 F2 (0.42) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7629140 0.82 NR1H2 (0.38) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7634060 0.82 NR1H2 (0.38) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7633886 0.82 NR1H2 (0.41) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7630720 0.81 NR1H2 (0.40) NR1H2NR1H3F2LMNAHPGD
SCHEMBL7632572 0.81 NR1H2 (0.37) NR1H2NR1H3F2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed