Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639645 | 0.89 | — | — | |
| SCHEMBL9812378 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1 | |
| SCHEMBL7634183 | 0.71 | — | — | |
| SCHEMBL578400 | 0.70 | — | — | |
| SCHEMBL2198815 | 0.67 | — | — | |
| 1,2-Dichloroethane SCHEMBL28113016 | 0.65 | — | — | |
| SCHEMBL1561895 | 0.64 | — | — | |
| SCHEMBL1867394 | 0.63 | — | — | |
| SCHEMBL21723228 | 0.63 | — | — | |
| SCHEMBL10944837 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350926-B1 | HYDROFLUORINATION OF CHLOROBUTANE OR CHLOROBUTENE | SYNGENTA LIMITED (GB) | 2002-02-26 | — | — | US | disclosed |
| EP-0853606-B1 | 1,1-DIFLUORO-1,4-DICHLOROBUTANE AND PROCESS FOR ITS PREPARATION | SYNGENTA LTD (GB) | 2001-09-26 | — | — | EP | disclosed |
| CN-1065520-C | 1,1-difluoro-1,4-dichlorobutane and process for its preparation | ZENECA LTD (GB) | 2001-05-09 | — | — | CN | disclosed |
| US-6075172-A | Chlorofluorohydrocarbon and process thereto | ZENECA LIMITED (GB) | 2000-06-13 | — | — | US | disclosed |
| EP-0970031-A1 | FLUORINATION PROCESS | ZENECA LIMITED (GB) | 2000-01-12 | — | — | EP | disclosed |
| US-5852222-A | Process | ZENECA LIMITED (GB) | 1998-12-22 | — | — | US | disclosed |
| CN-1196040-A | 1, 1-difluoro-1, 4-dichlorobutane and preparation method thereof | ZENECA LTD (GB) | 1998-10-14 | — | — | CN | disclosed |
| WO-1998040334-A1 | FLUORINATION PROCESS | ZENECA LIMITED (GB) | 1998-09-17 | — | — | WO | disclosed |
| EP-0853606-A1 | 1,1-DIFLUORO-1,4-DICHLOROBUTANE AND PROCESS FOR ITS PREPARATION | ZENECA LIMITED (GB) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997010192-A1 | 1,1-DIFLUORO-1,4-DICHLOROBUTANE AND PROCESS FOR ITS PREPARATION | ZENECA LIMITED (GB) | 1997-03-20 | — | — | WO | disclosed |