Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 3/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197356 | 0.76 | PNMT (0.39) | PNMTNPC1RAB9ASIGMAR1PGR | |
| SCHEMBL7580876 | 0.75 | PNMT (0.38) | PNMTNPC1RAB9ASIGMAR1PGR | |
| SCHEMBL7576895 | 0.73 | PNMT (0.37) | PNMTNPC1RAB9ASIGMAR1PGR | |
| SCHEMBL7577392 | 0.73 | PNMT (0.37) | PNMTNPC1RAB9ASIGMAR1PGR | |
| Hydrochloric Acid SCHEMBL7197359 | 0.73 | PNMT (0.41) | PNMTNPC1RAB9ASIGMAR1PGR | |
| SCHEMBL7584535 | 0.73 | PNMT (0.41) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL714249 | 0.73 | PNMT (0.42) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL396687 | 0.73 | PNMT (0.42) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL7578182 | 0.72 | PNMT (0.43) | PNMTNPC1RAB9APGRHTR7 | |
| SCHEMBL7575501 | 0.72 | PNMT (0.43) | PNMTNPC1RAB9APGRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365764-B1 | METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-04-02 | — | — | US | disclosed |