Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312851 | 0.87 | KDM4E (0.60) | TSHRGAAKDM4EFFAR1ALDH1A1 | |
| SCHEMBL8464596 | 0.84 | ALDH1A1 (0.55) | TSHRGAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8168167 | 0.83 | TSHR (0.68) | TSHRGAAKDM4EFFAR1ALDH1A1 | |
| SCHEMBL5575328 | 0.83 | GAA (0.78) | TSHRGAAKDM4EALDH1A1FLT3 | |
| SCHEMBL20471839 | 0.83 | TSHR (0.56) | TSHRGAAKDM4EL3MBTL1FLT3 | |
| SCHEMBL6422020 | 0.83 | KDM4E (0.52) | TSHRGAAKDM4EFFAR1ALDH1A1 | |
| SCHEMBL2980229 | 0.83 | TSHR (0.52) | TSHRGAAKDM4EFFAR1ALDH1A1 | |
| SCHEMBL8786560 | 0.83 | KDM4E (0.49) | TSHRGAAKDM4EFFAR1ALDH1A1 | |
| SCHEMBL6599952 | 0.83 | TSHR (0.56) | TSHRGAAKDM4EALDH1A1FLT3 | |
| SCHEMBL10737872 | 0.83 | GAA (0.60) | TSHRGAAKDM4EALDH1A1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111450716-A | Preparation of covalent cross-linked polymer-metal-organic cage composite membrane | 南开大学 | 2020-07-28 | — | — | CN | disclosed |
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | disclosed |
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | disclosed |
| US-9539336-B2 | Sialic acid derivatives | BROSSMER REINHARD (DE) | 2017-01-10 | — | — | US | disclosed |
| EP-2863925-B1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-09-14 | — | — | EP | disclosed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150174262-A1 | Sialic Acid Derivatives | BROSSMER REINHARD (DE) | 2015-06-25 | — | — | US | disclosed |
| EP-0722990-B1 | Thermoplastic resin compositions for use in integral molding with silicone rubber and integrally molded parts | SHINETSU CHEMICAL CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5989704-A | Integrally molded automotive waterproof connector comprising thermoplastic resin and oil-bleeding silicone rubber | YAZAKI CORPORATION (JP) | 1999-11-23 | — | — | US | disclosed |
| US-5879809-A | Thermoplastic resin/oil-bleeding silicone rubber integrally molded articles | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5792812-A | IMPROVING THE ADHESION TO SILICON RUBBER BY HYDROSILATION WITH ALIPHATIC UNSATURATED GROUP IN THERMOPLASTIC RESIN | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0598263-B1 | Organopolysiloxane modified polyesters and method for the preparation thereof | DOW CORNING TORAY SILICONE (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5552223-A | ROOM TEMPERATURE CURABLE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0722990-A2 | Thermoplastic resin compositions for use in integral molding with silicone rubber and integrally molded parts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-07-24 | — | — | EP | disclosed |
| EP-0598263-A1 | Organopolysiloxane modified polyesters and method for the preparation thereof | Dow Corning Toray Silicone Company, Limited (JP) | 1994-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174262-A1 | Sialic Acid Derivatives | NEU1, SIGLEC9, SIGLEC7 | TSHR 1042/4885GAA 86/4885KDM4E 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.