Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441579 | 0.90 | ORAI1 (0.41) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL8966998 | 0.75 | ORAI1 (0.42) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL6436492 | 0.69 | ORAI1 (0.41) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL27130231 | 0.68 | MEN1 (0.41) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| Water SCHEMBL28041769 | 0.67 | NPSR1 (0.37) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| Trimethylammonium SCHEMBL8966904 | 0.66 | ORAI1 (0.43) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL6434272 | 0.66 | — | — | |
| SCHEMBL8966469 | 0.65 | ORAI1 (0.38) | ORAI1ORAI2ORAI3TRPV6CA4 | |
| SCHEMBL8966866 | 0.65 | KMT2A (0.42) | ALDH1A1TSHRMEN1HTTKMT2A | |
| Water SCHEMBL27661286 | 0.65 | ORAI1 (0.38) | ORAI1ORAI2ORAI3TRPV6CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238989-A2 | Olefin polymerization catalyst and process for producing olefin polymer with the catalyst | Mitsui Chemicals, Inc. (JP) | 2002-09-11 | — | — | EP | disclosed |