SCHEMBL6441579

SCHEMBL6441579

CN(C)B(c1ccccc1)N(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.41
ORAI2 Q96SN7 3/20 0.41
ORAI3 Q9BRQ5 3/20 0.41
TRPV6 Q9H1D0 3/20 0.41
CA4 P22748 2/20 0.41
PCSK9 Q8NBP7 2/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
ENPP2 Q13822 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
KCNN4 O15554 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7635226 0.90 ORAI1 (0.39) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL6436492 0.77 ORAI1 (0.41) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL27130231 0.76 MEN1 (0.41) ORAI1ORAI2ORAI3TRPV6CA4
Trimethylammonium SCHEMBL8966904 0.73 ORAI1 (0.43) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL8966469 0.72 ORAI1 (0.38) ORAI1ORAI2ORAI3TRPV6CA4
Water SCHEMBL27661286 0.72 ORAI1 (0.38) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL8966998 0.72 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL27130255 0.69 CA4 (0.40) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL4266647 0.69 ALDH1A1 (0.41) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL6470522 0.65 CA4 (0.42) ORAI1ORAI2ORAI3TRPV6CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20220162205-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-05-26 US disclosed
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-0519496-B1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same TONEN CORP (JP) 1996-05-22 EP disclosed
EP-0404503-B1 Boron-containing, silicon nitride-based ceramic shaped body production process TONEN CORP (JP) 1996-03-06 EP disclosed
EP-0389084-B1 Process for producing a polyborosilazane TONEN CORP (JP) 1995-09-20 EP disclosed
US-5292830-A Silane, silazane, boron block crosslinked copolymers TONEN CORPORATION (JP) 1994-03-08 US disclosed
EP-0519496-A1 Thermosetting copolymers, silicon carbide-based fiber and processes for producing same Tonen Corporation (JP) 1992-12-23 EP disclosed
US-5128286-A BORON-CONTAINING, SILICON NITRIDE-BASED CERAMIC SHAPED BODY TONEN CORPORATION (JP) 1992-07-07 US disclosed
US-5030744-A Polyborosilazane and process for producing same TONEN CORPORATION (JP) 1991-07-09 US disclosed
EP-0404503-A1 Boron-containing, silicon nitride-based ceramic shaped body production process Tonen Corporation (JP) 1990-12-27 EP disclosed
EP-0389084-A2 Process for producing a polyborosilazane Tonen Corporation (JP) 1990-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220162205-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM ORAI1 618/4885ORAI2 45/4885ORAI3 81/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ORAI1 289/4885ORAI2 131/4885ORAI3 140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.