SCHEMBL7635527

SCHEMBL7635527

CC(=O)C1(C)CC=C2CCCCCCC2C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.32
CCR2 P41597 1/20 0.31
HPGD P15428 1/20 0.30
PTGS1 P23219 2/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28147948 0.67 KDM1A (0.36) CCR2HTT
SCHEMBL7638937 0.66 LMNA (0.34)
SCHEMBL7643088 0.66 LMNA (0.34)
SCHEMBL29380308 0.63
SCHEMBL11713974 0.62 TLR4 (0.32)
SCHEMBL235344 0.61 KDM1A (0.48) CCR2
SCHEMBL8361882 0.61 KDM1A (0.48) CCR2
SCHEMBL693557 0.61 KDM1A (0.48) CCR2
SCHEMBL123151 0.61 KDM1A (0.48) CCR2
SCHEMBL20552191 0.61 KDM1A (0.48) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962441-B1 Bicyclic aldehydes and ketones GIVAUDAN SA (CH) 2002-11-13 EP claimed
US-6242413-B1 ALSO 4-METHYLENESPIRO(2.6)NONANE COMPOUNDS GIVAUDAN ROURE (INTERNATIONAL) S.A. (CH) 2001-06-05 US claimed
EP-0962441-A1 Bicyclic aldehydes and ketones Givaudan Roure (International) S.A. (CH) 1999-12-08 EP claimed