SCHEMBL7635547

SCHEMBL7635547

CC1=CCC2CC1(OO)C2(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306646 0.63 MAPK1 (0.32) TSHRMAPK1
SCHEMBL20679699 0.61
SCHEMBL18695801 0.56
SCHEMBL3420633 0.53
SCHEMBL14315126 0.52 TSHR (0.32) TSHRMAPK1
SCHEMBL2428007 0.51 CYP17A1 (0.32)
Alpha-Pinene SCHEMBL338721 0.51 MAPK1 (0.92) TSHRMAPK1
SCHEMBL12324934 0.51 CYP17A1 (0.32)
SCHEMBL11875260 0.51 CCR2 (0.31)
Alpha-Pinene SCHEMBL23214400 0.49 MAPK1 (1.00) TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704491-B1 Silicone rubber composition DOW CORNING TORAY SILICONE (JP) 2002-07-17 EP disclosed
US-5605955-A CONTAINING POLYSILOXANE, ORGANIC PEROXIDE, REACTION PRODUCT OF UNSATURATED ESTER OF AROMATIC ACID AND ALKOXYSILANE; IMPROVED ADHESION TO SUBSTRATES DOW CORNING TORAY SILICONE CO., LTD. (JP) 1997-02-25 US disclosed
EP-0704491-A2 Silicone rubber composition Dow Corning Toray Silicone Company Ltd. (JP) 1996-04-03 EP disclosed