Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 20/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869106 | 0.79 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27558933 | 0.75 | PGR (0.49) | PGR | |
| SCHEMBL14818906 | 0.72 | PGR (0.39) | PGRNR3C1NR3C2AR | |
| SCHEMBL3379932 | 0.72 | PGR (0.39) | PGRNR3C1NR3C2AR | |
| SCHEMBL7167921 | 0.71 | PGR (0.60) | PGRNR3C1NR3C2AR | |
| SCHEMBL3380290 | 0.69 | PGR (0.37) | PGRNR3C1NR3C2AR | |
| SCHEMBL3872465 | 0.68 | PGR (0.82) | PGRNR3C1NR3C2AR | |
| SCHEMBL5125520 | 0.68 | PGR (0.66) | PGRNR3C1NR3C2AR | |
| SCHEMBL3379455 | 0.68 | NPC1 (0.44) | PGRNR3C1NR3C2AR | |
| SCHEMBL27579723 | 0.67 | PGR (0.73) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002543119-A | — | — | 2002-12-17 | — | — | JP | claimed |
| JP-2002543206-A | — | — | 2002-12-17 | — | — | JP | claimed |
| US-6399593-B1 | CONTRACEPTIVES | WYETH | 2002-06-04 | — | — | US | claimed |
| US-6369056-B1 | AGONISTS AND ANTAGONISTS OF THE PROGESTERONE RECEPTOR; CONTRACEPTIVES; 6-(3-CHLOROPHENYL)-4,4-DIMETHYL-1,4-DIHYDRO -3-OXA-1,8-DIAZA-NAPHTHALENE-2-ONE AND 6-CHLORO-4,4-DIMETHYL-1,4-DIHYDRO-3-OXA-1,5-DIAZA-NAPHTHALEN-2-ONE | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-09 | — | — | US | claimed |
| EP-1173208-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-01-23 | — | — | EP | claimed |
| EP-1173443-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | claimed |
| WO-2000066103-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| WO-2000066592-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| US-20020111355-A1 | Cyclic urea and cyclic amide derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6399593-B1 | CONTRACEPTIVES | WYETH | 2002-06-04 | — | — | US | disclosed |
| US-6369056-B1 | AGONISTS AND ANTAGONISTS OF THE PROGESTERONE RECEPTOR; CONTRACEPTIVES; 6-(3-CHLOROPHENYL)-4,4-DIMETHYL-1,4-DIHYDRO -3-OXA-1,8-DIAZA-NAPHTHALENE-2-ONE AND 6-CHLORO-4,4-DIMETHYL-1,4-DIHYDRO-3-OXA-1,5-DIAZA-NAPHTHALEN-2-ONE | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-09 | — | — | US | disclosed |
| EP-1173208-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1173443-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066103-A2 | CONTRACEPTIVE COMPOSITIONS CONTAINING CYCLIC UREA AND AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000066592-A1 | CYCLIC UREA AND CYCLIC AMIDE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111355-A1 | Cyclic urea and cyclic amide derivatives | PGR, GNRHR, FSHR | PGR 1/4885NR3C1 41/4885NR3C2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.