SCHEMBL7635755

SCHEMBL7635755

CC(C)(C)c1ccc(C(=O)OO[C]2CCCCC2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.47
MITF O75030 1/20 0.47
SLC6A2 P23975 1/20 0.47
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DHODH Q02127 2/20 0.44
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
ALDH1A1 P00352 3/20 0.43
HTT P42858 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PRSS1 P07477 1/20 0.43
ACR P10323 1/20 0.43
HDAC1 Q13547 1/20 0.42
HPGD P15428 2/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 2/20 0.41
TNF P01375 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625683 1.00 SMN1; SMN2 (0.47) SMN1; SMN2MITFSLC6A2MAPTTDP1
SCHEMBL7633813 0.98 MAPT (0.47) SMN1; SMN2MITFSLC6A2MAPTTDP1
SCHEMBL7629083 0.86 MAPT (0.51) SMN1; SMN2MITFSLC6A2MAPTTDP1
SCHEMBL7628178 0.84 MAPT (0.43) SMN1; SMN2MAPTTDP1L3MBTL1DHODH
SCHEMBL7631017 0.82 MEN1 (0.46) SMN1; SMN2MAPTTDP1L3MBTL1DHODH
SCHEMBL7631506 0.82 TP53 (0.43) SMN1; SMN2MITFSLC6A2MAPTTDP1
SCHEMBL7623860 0.82 TDP1 (0.48) SMN1; SMN2MAPTTDP1L3MBTL1ALDH1A1
SCHEMBL7625721 0.82 TDP1 (0.48) SMN1; SMN2MAPTTDP1L3MBTL1ALDH1A1
SCHEMBL7634239 0.81 ALDH1A1 (0.47) SMN1; SMN2TDP1L3MBTL1ALDH1A1MEN1
SCHEMBL7633619 0.81 ALDH1A1 (0.47) SMN1; SMN2TDP1L3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed