Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196580 | 0.95 | PTPN1 (0.43) | PTPN1GAAKMT2AMEN1BRD4 | |
| SCHEMBL7638237 | 0.88 | CYP4F2 (0.41) | PTPN1GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7641770 | 0.87 | PTPN1 (0.35) | PTPN1GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7636123 | 0.86 | GAA (0.39) | GAAKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7643260 | 0.84 | TDP1 (0.35) | PTPN1GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL23925764 | 0.78 | GAA (0.42) | GAAKMT2AMEN1PDE4DVCAM1 | |
| SCHEMBL6074895 | 0.77 | GAA (0.41) | PTPN1GAAKMT2AMEN1PDE4D | |
| SCHEMBL490767 | 0.76 | GAA (0.67) | GAAKMT2AMEN1VCAM1ALDH1A1 | |
| Methane SCHEMBL9226524 | 0.75 | GAA (0.65) | GAAKMT2AMEN1VCAM1ALDH1A1 | |
| SCHEMBL14342310 | 0.75 | GAA (0.53) | GAAKMT2AMEN1VCAM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015518-B1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SC HOLDING AG (CH) | 2002-05-15 | — | — | EP | disclosed |
| US-6323267-B1 | MIXING HIGH MOLECULAR WEIGHT ORGANIC OR INORGANIC MATERIAL WITH ISOXINDIGO COMPOUND | CIBA SPECIALTY CHEMICALS CORP. | 2001-11-27 | — | — | US | disclosed |