Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909636 | 0.88 | GAA (0.37) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL19325320 | 0.81 | GAA (0.39) | GAAKMT2AMEN1PDE4DVCAM1 | |
| SCHEMBL6074348 | 0.80 | GAA (0.37) | GAAKMT2AMEN1PDE4DALDH1A1 | |
| SCHEMBL15430202 | 0.80 | PDE4D (0.39) | GAAKMT2AMEN1PDE4DMAOB | |
| SCHEMBL19320502 | 0.79 | GAA (0.39) | GAAKMT2AMEN1PDE4DMAOB | |
| SCHEMBL15430206 | 0.79 | GAA (0.37) | GAAKMT2AMEN1PDE4DMAOB | |
| SCHEMBL19325319 | 0.77 | KMT2A (0.35) | GAAKMT2AMEN1PDE4DMAOB | |
| SCHEMBL8521462 | 0.77 | GAA (0.41) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL23925764 | 0.77 | GAA (0.42) | GAAKMT2AMEN1PDE4DVCAM1 | |
| SCHEMBL7636730 | 0.77 | PTPN1 (0.44) | GAAKMT2AMEN1PDE4DVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328218-B2 | Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material | BASF SE (DE) | 2016-05-03 | — | — | US | disclosed |
| US-9328218-B2 | Polyglycol bis-[3-(7-tert-butyl-2-oxo-3-phenyl-3H-benzofuran-5-yl-)propanoyl] derivatives as stabilizers of organic material | BASF SE (DE) | 2016-05-03 | — | — | US | disclosed |
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2015-07-09 | — | — | US | disclosed |
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2015-07-09 | — | — | US | disclosed |
| WO-2014009361-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | BASF SE (DE) | 2014-01-16 | — | — | WO | disclosed |
| US-20070037979-A1 | Preparation of rosuvastatin | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-02-15 | — | — | US | disclosed |
| US-7060425-B1 | Color photographic material | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-06-13 | — | — | US | disclosed |
| EP-1131674-B1 | COLOUR PHOTOGRAPHIC MATERIAL | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | EP | disclosed |
| US-6533825-B2 | For colouring/pigmenting high-molecular-weight organic material | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-03-18 | — | — | US | disclosed |
| US-20020095046-A1 | Dibenzonaphthyrones | NESVADBA PETER (CH) | 2002-07-18 | — | — | US | disclosed |
| EP-1015518-B1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SC HOLDING AG (CH) | 2002-05-15 | — | — | EP | disclosed |
| US-6323267-B1 | MIXING HIGH MOLECULAR WEIGHT ORGANIC OR INORGANIC MATERIAL WITH ISOXINDIGO COMPOUND | CIBA SPECIALTY CHEMICALS CORP. | 2001-11-27 | — | — | US | disclosed |
| EP-1131674-A1 | COLOUR PHOTOGRAPHIC MATERIAL | Ciba SC Holding AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| US-6281361-B1 | COLORING, PIGMENTING | CIBA SPECIALTY CHEMICALS CORP. | 2001-08-28 | — | — | US | disclosed |
| EP-1095041-A2 | DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL | Ciba SC Holding AG (CH) | 2001-05-02 | — | — | EP | disclosed |
| EP-1015518-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | Ciba SC Holding AG (CH) | 2000-07-05 | — | — | EP | disclosed |
| WO-2000023849-A1 | COLOUR PHOTOGRAPHIC MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-04-27 | — | — | WO | disclosed |
| WO-1999052909-A2 | DIBENZONAPHTHYRONES AND THEIR USE FOR COLOURING/PIGMENTING HIGH-MOLECULAR-WEIGHT ORGANIC MATERIAL | CIBA SPECIALTY CHEMICAL HOLDING INC. (CH) | 1999-10-21 | — | — | WO | disclosed |
| WO-1999013007-A1 | ISOXINDIGOS USEFUL AS COLORANTS AND PREPARATION THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191581-A1 | POLYGLYCOL BIS-[3-(7-TERT-BUTYL-2-OXO-3-PHENYL-3H-BENZOFURAN-5-YL-)PROPANOYL] DERIVATIVES AS STABILIZERS OF ORGANIC MATERIAL | H1-0, PCBP1, HEATR1 | GAA 624/4885KMT2A 3824/4885MEN1 3355/4885 |
| US-20020095046-A1 | Dibenzonaphthyrones | CYP1B1, CYP7B1, CYP1A1 | GAA 1464/4885KMT2A 1512/4885MEN1 218/4885 |
| US-20070037979-A1 | Preparation of rosuvastatin | HMGCR, PCSK9, PCSK7 | GAA 1145/4885KMT2A 2464/4885MEN1 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.