Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.45 |
| ▸ | BID | P55957 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871528 | 0.92 | TYR (0.53) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL8401820 | 0.87 | TYR (0.67) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL8402775 | 0.87 | TYR (0.67) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL5678803 | 0.85 | TYR (0.59) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL11079390 | 0.84 | PRKCI (0.47) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL574314 | 0.84 | BID (0.59) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL27523547 | 0.84 | BID (0.59) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL27344804 | 0.81 | BID (0.57) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL11616253 | 0.81 | TYR (0.46) | TYRTP53CYP3A4MEN1ALOX5 | |
| SCHEMBL11615877 | 0.81 | TYR (0.46) | TYRTP53CYP3A4MEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355754-B1 | 4,6-DIBROMO-2-ALKYL PHENYL ACRYLATE AND AROMATIC (METH)ACRYLATE COMONOMERS; OPTICS, LOW MELTING | 3M INNOVATIVE PROPERTIES COMPANY | 2002-03-12 | — | — | US | disclosed |