SCHEMBL27344804

SCHEMBL27344804

CCCCCc1cccc(O)c1Br

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 5/20 0.57
MCL1 Q07820 5/20 0.57
BCL2L1 Q07817 4/20 0.57
BAK1 Q16611 4/20 0.57
KAT8 Q9H7Z6 3/20 0.57
SAE1 Q9UBE0 2/20 0.57
EP300 Q09472 2/20 0.57
KAT5 Q92993 2/20 0.57
PPARG P37231 1/20 0.57
PPARA Q07869 1/20 0.57
KAT2A Q92830 1/20 0.57
KAT2B Q92831 1/20 0.57
ALOX5 P09917 2/20 0.51
PTGS2 P35354 1/20 0.51
F7 P08709 3/20 0.49
F3 P13726 3/20 0.49
MMP2 P08253 2/20 0.49
MAPT P10636 2/20 0.49
ALOX15 P16050 2/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27523547 0.98 BID (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL574314 0.98 BID (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL16429384 0.94 BID (0.50) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL27216661 0.86 GABRA1 (0.46) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL31634508 0.86 GABRA1 (0.46) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL28321854 0.86 GABRA1 (0.56) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL6429980 0.84 BID (0.47) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL31075131 0.84 LIPG (0.55) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL7636899 0.81 TYR (0.59) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL70878 0.81 IAPP (0.65) BIDMCL1BCL2L1BAK1KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1953658-A Antimicrobial silicon oxide flakes CIBA SC HOLDING AG (CH) 2007-04-25 CN claimed
CN-110087634-A Methods of providing oral care benefits 费丁制药联合股份有限公司 2019-08-02 CN disclosed
CN-109843255-A Ethanol-reducing mouthwash formulation 强生消费者公司 2019-06-04 CN disclosed
CN-109414432-A Antimicrobial compounds and methods of use thereof 港大科桥有限公司 2019-03-01 CN disclosed
CN-109071682-A Home care compositions 赫尔克里士有限公司 2018-12-21 CN disclosed
CN-109054378-A The antimicrobial acivity of biocide is improved with polymer 巴斯夫欧洲公司 2018-12-21 CN disclosed
CN-108024563-A Improve the increased biomembrane composite inhibiting of weight in domestic animal 艾索生物医药公司 2018-05-11 CN disclosed
CN-105142601-B Oral care composition 强生消费者公司 2018-01-05 CN disclosed
CN-107105749-A Antimicrobial compounds and compositions and uses thereof 阿克索生物医药公司 2017-08-29 CN disclosed
CN-106823012-A Medical material with bacteria resistance function and preparation method thereof, application 沈坤 2017-06-13 CN disclosed
CN-104797236-A Oral care compositions MCNEIL PPC INC 2015-07-22 CN disclosed
CN-104349669-A Use of vanadium-containing particles as biocide BASF SE 2015-02-11 CN disclosed
CN-103025158-A Methods and coatings for treating biofilms HARVARD COLLEGE 2013-04-03 CN disclosed
CN-102223903-A Medical adhesive composition ETHICON INC 2011-10-19 CN disclosed
CN-101802316-A Improvements in lavatory treatment devices RECKITT BENCKISER INC 2010-08-11 CN disclosed
CN-1953658-A Antimicrobial silicon oxide flakes CIBA SC HOLDING AG (CH) 2007-04-25 CN disclosed
CN-1466621-A Hard surface cleaning and disinfecting compositions 雷克特本克斯尔有限公司 2004-01-07 CN disclosed
CN-1048867-C Tooth cleaning agent COLGATE PALMOLIVE CO (US) 2000-02-02 CN disclosed
CN-1045533-C Continuous process for making a non-newtonian paste or cream like material COLGATE PALMOLIVE CO (US) 1999-10-13 CN disclosed
CN-1083700-A Make the continuation method of non newtonian type cream, white shape goods COLGATE PALMOLIVE CO (US) 1994-03-16 CN disclosed