⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859934 | 0.75 | — | — | |
| SCHEMBL5533269 | 0.72 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL5540161 | 0.72 | TDP1 (0.39) | — | |
| SCHEMBL19270737 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL10100069 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL19275335 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL19270736 | 0.71 | FAAH (0.32) | — | |
| SCHEMBL31425601 | 0.70 | TP53 (0.35) | — | |
| SCHEMBL13355778 | 0.70 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL13355733 | 0.70 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140065-A4 | USE OF GAMMA-TOCOPHEROL AND ITS OXIDATIVE METABOLITE LLU-ALPHA IN THE TREATMENT OF DISEASE | UNIV LOMA LINDA MED (US) | 2002-10-16 | — | — | EP | disclosed |
| EP-1140065-A1 | USE OF GAMMA-TOCOPHEROL AND ITS OXIDATIVE METABOLITE LLU-ALPHA IN THE TREATMENT OF DISEASE | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035444-A1 | USE OF η-TOCOPHEROL AND ITS OXIDATIVE METABOLITE LLU-α IN THE TREATMENT OF DISEASE | LOMA LINDA UNIVERSITY MEDICAL CENTER (US) | 2000-06-22 | — | — | WO | disclosed |