Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637266 | 1.00 | LMNA (0.45) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL313119 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7638735 | 0.90 | LMNA (0.57) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL312263 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL313679 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL312262 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7641168 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7640266 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7641165 | 0.89 | LMNA (0.44) | LMNAKMT2APOLBALDH1A1TSHR | |
| SCHEMBL7642929 | 0.88 | LMNA (0.50) | LMNAKMT2APOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462183-B1 | SOLID PHASE OLIGOSACCHARIDE SYNTHESIS | ALCHEMIA PTY LTD (AU) | 2002-10-08 | — | — | US | disclosed |