1,4-Butanediol

1,4-Butanediol

SCHEMBL7637693

CC(O)COC(C)CO.OCCCCO

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,6-Hexanediol SCHEMBL10789900 0.98 TDP1 (0.44) TDP1MAPK1HSD17B10
1,4-Butanediol SCHEMBL3063848 0.98 TDP1 (0.44) TDP1MAPK1HSD17B10
1,4-Butanediol SCHEMBL2578824 0.96 TDP1 (0.47) TDP1MAPK1HSD17B10
1,3-Propanediol SCHEMBL9578876 0.95 TDP1 (0.45) TDP1MAPK1HSD17B10
1,6-Hexanediol SCHEMBL8847195 0.94 TDP1 (0.46) TDP1MAPK1HSD17B10
1,6-Hexanediol SCHEMBL16970401 0.94 TDP1 (0.46) TDP1MAPK1HSD17B10
1,3-Propanediol SCHEMBL17472950 0.91 TDP1 (0.47) TDP1MAPK1HSD17B10
Ethylene Glycol SCHEMBL1412484 0.91 TDP1 (0.48) TDP1MAPK1HSD17B10
Ethylene Glycol SCHEMBL3058484 0.91 TDP1 (0.48) TDP1MAPK1HSD17B10
SCHEMBL23248656 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113980252-A Continuous production method of modified poly (butylene succinate) 上海师范大学 2022-01-28 CN claimed
US-8524258-B2 Structured lotions JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2013-09-03 US claimed
EP-0593459-A1 ANTI-LICE TREATMENT COMPOSITIONS. PROCTER & GAMBLE (US) 1994-04-27 EP claimed
EP-0359625-B1 Self-adhesive device for transdermal administration of an active agent LHD LAB HYGIENE DIETETIQUE (FR) 1993-12-15 EP claimed
EP-0593459-A4 ANTI-LICE TREATMENT COMPOSITIONS. PROCTER & GAMBLE (US) 1993-02-03 EP claimed
WO-1991016032-A1 ANTI-LICE TREATMENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO claimed
EP-0359625-A1 Self-adhesive device for transdermal administration of an active agent LABORATOIRES D'HYGIENE ET DE DIETETIQUE (FR) 1990-03-21 EP claimed
US-20240074558-A1 PORTABLE HAIR PRINTER AND PRINTING METHOD USING SAME PRINKER KOREA INC. (KR) 2024-03-07 US disclosed
US-20230301880-A1 INK COMPOSITION FOR HAIR DYEING, FILM FOR HAIR DYEING, FILM CARTRIDGE FOR HAIR DYEING, AND PRINTER FOR HAIR DYEING PRINKER KOREA INC. (KR) 2023-09-28 US disclosed
WO-2021056412-A1 TWO-PART COMPOSITION FOR CARING FOR KERATIN MATERIALS L'OREAL (FR) 2021-04-01 WO disclosed
CN-1679500-A Liquid cosmetics SHISEIDO CO LTD (JP) 2005-10-12 CN disclosed
US-6495159-B2 FOR ADMINISTERING A VOMITING DEPRESSANT AT THE TIME OF CHEMOTHERAPY OF CANCER; DRUG DELIVERY HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2002-12-17 US disclosed
US-20020102290-A1 TRANSDERMAL PREPARATION CONTAINING SEROTONIN RECEPTOR ANTAGONIST HISAMITZU PHARMACEUTICAL CO., INC. (JP) 2002-08-01 US disclosed