SCHEMBL7637779

SCHEMBL7637779

CN/C(=N\C#N)Nc1ccc(Cl)nc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNJ11 Q14654 12/20 0.43
KCNQ3 O43525 7/20 0.42
KCNQ2 O43526 7/20 0.42
KCNE1 P15382 3/20 0.42
KCNQ1 P51787 3/20 0.42
BACE1 P56817 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637789 1.00 KCNJ11 (0.43) KCNJ11KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL29345715 0.80 ALDH1A1 (0.49)
SCHEMBL4683458 0.79 KCNQ3 (0.44) KCNQ3KCNQ2KCNE1KCNQ1BACE1
SCHEMBL4683461 0.79 KCNQ3 (0.44) KCNQ3KCNQ2KCNE1KCNQ1BACE1
SCHEMBL4679225 0.78 KCNQ3 (0.41) KCNJ11KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL2969083 0.78 KCNQ3 (0.41) KCNJ11KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL7636310 0.76 ALDH1A1 (0.43)
SCHEMBL7636313 0.76 ALDH1A1 (0.43)
SCHEMBL9901685 0.75 KDM4E (0.39) KCNJ11KCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL9901682 0.75 KDM4E (0.39) KCNJ11KCNQ3KCNQ2KCNE1KCNQ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140350-A APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US claimed
US-6403058-B1 CONTROLLING TERMITES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-11 US disclosed
US-6391327-B1 SYNERGISTIC PESTICIDAL COMPOSITION COMPRISING PRALLETHRIN AND NEONICOTINOID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-05-21 US disclosed
US-6284782-B1 INSECTICIDES; SYNERGISTIC MIXTURES SUMITOMO CHEMICAL CO., LTD. (JP) 2001-09-04 US disclosed
US-6255340-B1 SYNERGISTIC MIXTURE OF PRALLETHRIN AND A NEONICOTINOID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-03 US disclosed
EP-0665222-B1 Guanidine derivatives, their production and insecticides TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-06-20 EP disclosed
US-6201017-B1 TOPICALLY APPLYING TO ANIMAL A LIQUID MIXTURE COMPRISING 1-(TETRAHYDRUFURAN-3-YL)METHYL-3-METHYL-2-NITROGUANIDINE, A GLYCOL OR ITS MONOALKYL ETHER AND A SOLVENT TO CONTROL FLEAS, LICE, TICKS SUMITOMO CHEMICAL CO., LTD. (JP) 2001-03-13 US disclosed
US-6140350-A APPLYING NEONICOTINOID COMPOUND FOR CONTROLLING ECTOPARASITES THROUGH BLOOD OF A HOST ANIMAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed
EP-0976328-A2 Ectoparasite controlling agent for animals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
EP-0966961-A1 Method for controlling ectoparasites SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-29 EP disclosed
US-5633375-A NONTOXIC TO HUMNAS, ANIMALS, FISH TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-05-27 US disclosed
US-5489603-A CONTAINING NITROGEN HETEROCYCLIC RINGS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-06 US disclosed
EP-0493369-B1 Guanidine derivatives, their production and insecticides TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-11-08 EP disclosed
EP-0665222-A1 Guanidine derivatives, their production and insecticides Takeda Chemical Industries, Ltd. (JP) 1995-08-02 EP disclosed
EP-0493369-A1 Guanidine derivatives, their production and insecticides Takeda Chemical Industries, Ltd. (JP) 1992-07-01 EP disclosed
EP-0376279-A2 Guanidine derivatives, their production and insecticides Takeda Chemical Industries, Ltd. (JP) 1990-07-04 EP disclosed