SCHEMBL7637844

SCHEMBL7637844

CCCCCCCCCCCCCCCCCCc1c(C(=O)O)c(C(=O)O)cc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 4/20 0.45
GCGR P47871 2/20 0.45
KAT8 Q9H7Z6 4/20 0.43
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
PPARA Q07869 2/20 0.43
PPARG P37231 1/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
RARA P10276 1/20 0.42
RARG P13631 1/20 0.42
SLC37A4 O43826 1/20 0.42
PTPN11 Q06124 1/20 0.42
PTGES O14684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624669 0.82 RARB (0.50) RARBKAT8BIDMCL1BCL2L1
SCHEMBL8634569 0.82 RARB (0.50) RARBKAT8BIDMCL1BCL2L1
SCHEMBL9452103 0.80 ALDH1A1 (0.41)
SCHEMBL28070435 0.80 GCGR (0.50) RARBGCGRKAT8BIDMCL1
SCHEMBL4660506 0.79 KAT8 (0.51) RARBKAT8BIDMCL1BCL2L1
SCHEMBL28707800 0.77 GCGR (0.51) RARBGCGRKAT8BIDMCL1
SCHEMBL28134037 0.77 RARB (0.46) RARBKAT8BIDMCL1BCL2L1
SCHEMBL9066218 0.77 BID (0.48) RARBGCGRKAT8BIDMCL1
Hexane SCHEMBL28401791 0.76 CNR2 (0.45) KAT8BIDMCL1BCL2L1BAK1
Biphenyl SCHEMBL28243513 0.76 PPARA (0.51) RARBKAT8BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6346574-B1 Fire retardance-imparting additive ASAHI KASEI KABUSHIKI KAISHA (JP) 2002-02-12 US disclosed
EP-1125984-A1 Aromatic polycarbonate-styrene polymer resin composition Asahi Kasei Kabushiki Kaisha (JP) 2001-08-22 EP disclosed
US-6069206-A COMPATIBILITY AGENT COMPRISING SPECIFIED COPOLYMER OF AROMATIC VINYL MONOMER AND POLYMERIZABLE MONOMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-05-30 US disclosed
US-5900446-A CONTAINING A COMPATIBILITY AGENT; ADDITION-CONDENSATION COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-05-04 US disclosed
EP-0767215-A1 AROMATIC POLYCARBONATE-STYRENE POLYMER RESIN COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-04-09 EP disclosed