Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL5884204 | 0.96 | — | — | |
| Lactic Acid SCHEMBL28579995 | 0.96 | TP53 (0.85) | TP53TSHRSLC7A5OR51E2 | |
| Lactic Acid SCHEMBL1663943 | 0.96 | — | — | |
| Lactic Acid SCHEMBL216439 | 0.96 | — | — | |
| Lactic Acid SCHEMBL316633 | 0.96 | — | — | |
| Lactic Acid SCHEMBL11059474 | 0.96 | TP53 (0.85) | TP53TSHRSLC7A5OR51E2 | |
| Lactic Acid SCHEMBL10320996 | 0.96 | — | — | |
| Lactic Acid SCHEMBL22345879 | 0.93 | TP53 (0.79) | TP53TSHRSLC7A5RNPEPOR51E2 | |
| Lactic Acid SCHEMBL7638405 | 0.93 | TP53 (0.79) | TP53TSHRSLC7A5RNPEPOR51E2 | |
| Lactic Acid SCHEMBL28669832 | 0.93 | TP53 (0.79) | TP53TSHRSLC7A5RNPEPOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346570-B1 | COMPOSITION COMPRISING UNIFORM MIXTURE OF MODIFIED POLYVINYL ALCOHOL CONTAINING ALPHA-OLEFIN UNITS WITH NOT MORE THAN 4 CARBON ATOMS AND/OR SILYL GROUPS AND ORGANOTITANIUM COMPOUND HAVING CHELATING LIGAND AT SPECIFIED BLEND RATIO | KURARAY CO., LTD. (JP) | 2002-02-12 | — | — | US | disclosed |