Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816125 | 0.90 | RORC (0.58) | RORCKDRL3MBTL1MEN1KMT2A | |
| SCHEMBL6815377 | 0.89 | RORC (0.66) | RORCL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL6814916 | 0.86 | RORC (0.60) | RORCKDRHTR2AHTR2CL3MBTL1 | |
| SCHEMBL6811046 | 0.85 | RORC (0.64) | RORCL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL6816231 | 0.85 | RORC (0.84) | RORCL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL7638372 | 0.84 | RORC (0.55) | RORCKDRHTR2AHTR2CMEN1 | |
| SCHEMBL7908567 | 0.83 | RORC (0.61) | RORCL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL3865174 | 0.79 | KDR (0.62) | RORCKDRHTR2AHTR2CKDM4E | |
| SCHEMBL7661021 | 0.79 | POLB (0.50) | RORCMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6810838 | 0.78 | RORC (0.61) | RORCL3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462055-B2 | VIRICIDES | WYETH | 2002-10-08 | — | — | US | disclosed |
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |