Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SAT1 | P21673 | 3/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270457 | 0.98 | CYP2C19 (0.46) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL7647790 | 0.96 | CYP2C19 (0.44) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Methylamine SCHEMBL11311742 | 0.94 | CYP2C19 (0.42) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL21359747 | 0.94 | CYP2C19 (0.48) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL2831239 | 0.91 | CYP2C19 (0.48) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL27224880 | 0.90 | CYP2C19 (0.39) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL7993874 | 0.89 | CYP2C19 (0.46) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL57190 | 0.89 | CYP2C19 (0.38) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| SCHEMBL10899998 | 0.88 | CYP2C19 (0.38) | CYP2C19MEN1GLAKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL28741000 | 0.86 | CYP2C19 (0.36) | CYP2C19MEN1GLAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486288-B1 | Crosslinkable organopolysiloxane compositions | WACKER-CHEMIE GMBH (DE) | 2002-11-26 | — | — | US | disclosed |