Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098465 | 1.00 | — | — | |
| SCHEMBL2852656 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL29166558 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL2501737 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL7070069 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL7639781 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL2501718 | 1.00 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| Ethane SCHEMBL10523003 | 0.97 | OPRM1 (0.52) | OPRM1SPHK1MAPTCYP2D6LMNA | |
| SCHEMBL1315066 | 0.97 | — | — | |
| Ethane SCHEMBL10525246 | 0.94 | OPRM1 (0.55) | OPRM1SPHK1MAPTCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6464962-B2 | N,N-BIS(2-HYDROXYETHYL)ALKYLAMINE HYDROFLUORIDE PREPARED BY REACTING THE CORRESPONDING AMINE WITH HYDROGEN FLUORIDE; EFFICIENT, EASY TO MAKE; BACTERIOSTAT FOR TOOTHPASTE, MOUTH RINSES | GABA INTERNATIONAL AG (CH) | 2002-10-15 | — | — | US | disclosed |
| US-20010006622-A1 | N-ALKYLDIETHANOLAMINE HYDROFLUORIDES AND ORAL HYGIENE COMPOSITIONS CONTAINING THEM | GABA INTERNATIONAL AG (CH) | 2001-07-05 | — | — | US | disclosed |
| US-5744114-A | Method of preparing dentifrice-compatible silica particulates | RHONE-POULENC CHIMIE (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5698327-A | ZINC IS CHEMICALLY BONDED TO SURFACE OF SILICA PARTICLES | RHONE-POULENC CHIMIE (FR) | 1997-12-16 | — | — | US | disclosed |
| US-5616316-A | REACTING SILICATE WITH ACID TO FORM AQUEOUS SUSPENSION OF SILICA, AGING, SEPARATING | RHONE-POULENC CHIMIE (FR) | 1997-04-01 | — | — | US | disclosed |
| US-5614177-A | FROM SILICATE AND ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5614176-A | REACTING A SILICATE AND AN ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-25 | — | — | US | disclosed |
| US-5612020-A | SILICATE AND ACID | RHONE-POULENC CHIMIE (FR) | 1997-03-18 | — | — | US | disclosed |
| US-5413844-A | Process for the preparation of zinc/dentifrice-compatible silica particulates | RHONE-POULENC CHIMIE (FR) | 1995-05-09 | — | — | US | disclosed |
| US-5286478-A | Having unique surface chemistry, specified number of hydroxyl functions and zero charge point | RHONE-POULENC CHIMIE (FR) | 1994-02-15 | — | — | US | disclosed |
| CN-1020548-C | Toothpaste composition containing silica compatible with zinc | RHONE POULENC CHIMIE (FR) | 1993-05-12 | — | — | CN | disclosed |
| CN-1054533-A | The toothpaste component that contains Silicon stone that can be compatible with zinc | RHONE POULENC CHIMIE (FR) | 1991-09-18 | — | — | CN | disclosed |