Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611650 | 0.91 | ADRB3 (0.58) | ADRB3ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL7610557 | 0.90 | ADRB3 (0.74) | ADRB3ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL7612142 | 0.84 | ADRB3 (0.52) | ADRB3ADRB2ADRB1 | |
| SCHEMBL7608782 | 0.80 | ADRB3 (0.75) | ADRB3ADRB2ADRB1 | |
| SCHEMBL20049935 | 0.79 | KMT2A (0.67) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7608477 | 0.79 | ADRB3 (0.59) | ADRB3ADRB2ADRB1KMT2AALDH1A1 | |
| SCHEMBL7610759 | 0.78 | ADRB3 (0.57) | ADRB3ADRB2ADRB1KMT2AMEN1 | |
| SCHEMBL9054230 | 0.78 | ADRB3 (0.70) | ADRB3ADRB2ADRB1 | |
| SCHEMBL14030801 | 0.77 | ADRB2 (0.59) | ADRB3ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL7608362 | 0.77 | ADRB2 (0.50) | ADRB3ADRB2ADRB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |