Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638828 | 0.91 | ESR1 (0.44) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10579295 | 0.90 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9356118 | 0.90 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL1790604 | 0.80 | HSPA5 (0.33) | — | |
| SCHEMBL11025708 | 0.78 | HSPA5 (0.33) | — | |
| SCHEMBL337109 | 0.78 | SMN1; SMN2 (0.32) | ALDH1A1 | |
| SCHEMBL1074117 | 0.78 | RXRA (0.31) | — | |
| SCHEMBL4659187 | 0.77 | CNR2 (0.38) | — | |
| SCHEMBL7643709 | 0.76 | ESR1 (0.53) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL10607967 | 0.75 | CNR2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0856526-B1 | OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME | CHISSO CORP (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-6313225-B2 | High melt tension, high crystallization temperature; hollow moldings | CHISSO CORPORATION (JP) | 2001-11-06 | — | — | US | disclosed |
| US-20010004657-A1 | OLEFIN(CO-) POLYMER COMPOSITIONS AND METHOD FOR PRODUCING THE SAME ANDCATALYST FOR OLEFIN (CO-) POLYMERIZATION AND METHOD FOR PRODUCING THE SAME | CHISSO CORPORATION (JP) | 2001-06-21 | — | — | US | disclosed |
| US-6156845-A | Polyolefin composition and method of making | CHISSO CORPORATION (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0856526-A1 | OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PRODUCING THE SAME, CATALYST FOR (CO)POLYMERIZING OLEFIN, AND PROCESS FOR PRODUCING THE SAME | CHISSO CORPORATION (JP) | 1998-08-05 | — | — | EP | disclosed |