SCHEMBL7639043

SCHEMBL7639043

COCCc1nc2c(N)nc3c(c2n1CCCCN(C(N)=S)c1ccccc1)CCCC3

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7157098 0.92 TLR7 (0.47) TLR7
SCHEMBL7101492 0.83 TLR7 (0.44) TLR7
SCHEMBL5750376 0.81 GAA (0.41) TLR7
SCHEMBL5750020 0.80 TLR7 (0.48) TLR7
SCHEMBL5746088 0.80 TLR7 (0.44) TLR7
SCHEMBL5748494 0.79 TLR7 (0.41) TLR7
SCHEMBL3823104 0.79 TLR7 (0.43) TLR7
SCHEMBL3865322 0.79 TLR7 (0.48) TLR7
SCHEMBL3872445 0.78 TLR7 (0.39) TLR7
SCHEMBL5773579 0.78 TLR7 (0.44) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1198232-A4 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP claimed
EP-1198232-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-04-24 EP claimed
WO-2000076518-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO claimed