Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008214 | 1.00 | RARB (0.38) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL11744281 | 0.88 | MMP13 (0.42) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL11750452 | 0.86 | NR5A1 (0.42) | RARBHTR1AHTR1DHTR1BTDP1 | |
| SCHEMBL1100667 | 0.86 | RARB (0.39) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL17433581 | 0.86 | RARB (0.39) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL108804 | 0.86 | RARB (0.39) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL9008236 | 0.85 | RARB (0.40) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL28228053 | 0.84 | RARB (0.38) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL7743402 | 0.84 | RARB (0.38) | RARBHTR1AHTR1DHTR1BMEN1 | |
| SCHEMBL2918907 | 0.84 | RARB (0.36) | RARBHTR1AHTR1DHTR1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479572-B1 | Thermoplastic molding materials stable to thermal oxidation | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
| US-4255321-A | BLENDS WITH HIGH IMPACT-STRENGTH BUTADIENE-STYRENE COPOLYMER INCLUDE A SYNERGISTIC MIXTURE OF A METAL SULFIDE AND ZINC OXIDE; ENGINEERING THERMOPLASTICS | GENERAL ELECTRIC COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| US-4123474-A | STABILIZED THERMOPLASTIC MOLDING MATERIAL | GENERAL ELECTRIC COMPANY (US) | 1978-10-31 | — | — | US | disclosed |