SCHEMBL7640153

SCHEMBL7640153

C=C(C)C(=O)OC[Si](OC)(OC)OCC

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 4/20 0.41
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16286588 0.95 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL80190 0.91 THRB (0.50) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL29005374 0.87 THRB (0.47) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL82401 0.87 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL7641737 0.84 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7638655 0.84 THRB (0.44) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7643205 0.83 THRB (0.51) THRBTSHRALDH1A1
SCHEMBL7639156 0.83 THRB (0.51) THRBTSHRALDH1A1
SCHEMBL23031115 0.83 THRB (0.42) THRBTSHRALDH1A1
SCHEMBL3417371 0.80 TSHR (0.51) THRBTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140285760-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-09-25 US disclosed
US-6399212-B1 COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE NIPPON SHEET GLASS CO., LTD. (JP) 2002-06-04 US disclosed
EP-1094090-A2 Silicon dioxide-coated polyolefin resin and process for its production NIPPON SHEET GLASS CO. LTD. (JP) 2001-04-25 EP disclosed