Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 1.00 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29842378 | 1.00 | NOTUM (1.00) | NOTUMKEAP1NPC1MAPTCYP19A1 | |
| SCHEMBL14961974 | 0.83 | NOTUM (0.75) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL30413216 | 0.82 | NOTUM (0.69) | NOTUMKEAP1NPC1MAPTCYP19A1 | |
| SCHEMBL28166936 | 0.80 | NOTUM (0.67) | NOTUMKEAP1MAPTCYP19A1CA1 | |
| SCHEMBL28266369 | 0.79 | NOTUM (0.65) | NOTUMKEAP1 | |
| SCHEMBL29471936 | 0.79 | NOTUM (0.65) | NOTUMKEAP1 | |
| SCHEMBL670667 | 0.79 | NOTUM (0.65) | NOTUMKEAP1CYP19A1MGLLALDH1A1 | |
| SCHEMBL29084891 | 0.79 | NOTUM (0.65) | NOTUMKEAP1MAPTCYP19A1CA1 | |
| SCHEMBL29084878 | 0.77 | NOTUM (0.63) | NOTUMKEAP1CYP19A1MGLLALDH1A1 | |
| SCHEMBL29635591 | 0.77 | NOTUM (0.63) | NOTUMNPC1MAPTMGLLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210151696-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANOMETALLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-05-20 | — | — | US | disclosed |
| CN-103201261-A | Lactam derivatives as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-07-10 | — | — | CN | disclosed |
| EP-1169360-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058373-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |