SCHEMBL7640447

SCHEMBL7640447

CC1(Cc2ccc(O)cc2)CCCC(c2ccc(O)cc2)C1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 18/20 0.47
TRPA1 O75762 1/20 0.44
ESR1 P03372 10/20 0.42
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3148071 0.78 ESR2 (0.56) ESR2TRPA1ESR1CYP3A4CYP2C9
SCHEMBL23542798 0.77 ESR1 (0.47) ESR2ESR1
SCHEMBL151163 0.77 ESR2 (0.44) ESR2ESR1CYP3A4CYP2C9
SCHEMBL9077094 0.76 ESR1 (0.46) ESR2ESR1
SCHEMBL16788269 0.74 ESR2 (0.51) ESR2TRPA1ESR1CYP3A4CYP2C9
SCHEMBL18257873 0.71 ESR2 (0.66) ESR2ESR1CYP3A4CYP2C9CYP2D6
SCHEMBL9185040 0.71 ESR2 (0.44) ESR2TRPA1ESR1CYP3A4CYP2C9
SCHEMBL16581404 0.70 ESR2 (0.55) ESR2TRPA1ESR1CYP3A4CYP2C9
SCHEMBL18257842 0.70 ESR2 (0.86) ESR2TRPA1ESR1CYP3A4CYP2C9
SCHEMBL18257845 0.70 ESR2 (0.86) ESR2TRPA1ESR1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337371-B2 MIXTURE TECHNO POLYMER CO., LTD. (JP) 2002-01-08 US claimed
US-6262173-B1 HAVING IMPACT RESISTANCE, HEAT RESISTANCE, CHEMICAL RESISTANCE AND WEATHER RESISTANCE TECHNO POLYMER CO., LTD. (JP) 2001-07-17 US claimed
US-6337371-B2 MIXTURE TECHNO POLYMER CO., LTD. (JP) 2002-01-08 US disclosed
US-20010011116-A1 Thermoplastic resin composition having excellent long-term heat-aging properties TECHNO POLYMER CO., LTD. 2001-08-02 US disclosed
US-6262173-B1 HAVING IMPACT RESISTANCE, HEAT RESISTANCE, CHEMICAL RESISTANCE AND WEATHER RESISTANCE TECHNO POLYMER CO., LTD. (JP) 2001-07-17 US disclosed
EP-0972804-A2 Thermoplastic resin composition having long-term-heat-aging properties Techno Polymer Co., Ltd. (JP) 2000-01-19 EP disclosed