Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 18/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 9/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257873 | 0.86 | ESR2 (0.66) | ESR2ESR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL22299932 | 0.84 | TRPA1 (0.49) | ESR2TRPA1 | |
| SCHEMBL30074982 | 0.82 | TRPA1 (0.47) | ESR2TRPA1 | |
| SCHEMBL16788269 | 0.81 | ESR2 (0.51) | ESR2TRPA1ESR1CYP3A4CYP2D6 | |
| SCHEMBL6139859 | 0.80 | TRPA1 (0.46) | ESR2TRPA1 | |
| SCHEMBL7640447 | 0.78 | ESR2 (0.47) | ESR2TRPA1ESR1CYP3A4CYP2D6 | |
| SCHEMBL18257845 | 0.77 | ESR2 (0.86) | ESR2TRPA1ESR1CYP3A4CYP2D6 | |
| SCHEMBL18257842 | 0.77 | ESR2 (0.86) | ESR2TRPA1ESR1CYP3A4CYP2D6 | |
| SCHEMBL16581404 | 0.77 | ESR2 (0.55) | ESR2TRPA1ESR1CYP3A4CYP2D6 | |
| SCHEMBL3148250 | 0.77 | ESR2 (0.75) | ESR2ESR1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114302905-A | Thermoplastic resin composition and molded article | 三菱化学株式会社 | 2022-04-08 | — | — | CN | disclosed |
| WO-2021039970-A1 | THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE | 三菱ケミカル株式会社 | 2021-03-04 | — | — | WO | disclosed |
| EP-2137193-B1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI SA (FR) | 2017-08-09 | — | — | EP | disclosed |
| CN-105431488-B | Thin walled optical component poly carbonate resin composition and thin walled optical component | 三菱工程塑料株式会社 | 2017-06-13 | — | — | CN | disclosed |
| CN-104447792-A | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI AVENTIS | 2015-03-25 | — | — | CN | disclosed |
| US-8642603-B2 | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI (FR) | 2014-02-04 | — | — | US | disclosed |
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-25 | — | — | US | disclosed |
| EP-2137193-A2 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | Sanofi-Aventis (FR) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008112483-A2 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2008-09-18 | — | — | WO | disclosed |
| EP-1927098-A2 | ILLUMINATING DEVICE COMBINING A WHITE LED AND A DIFFUSING SHEET | ARKEMA France (FR) | 2008-06-04 | — | — | EP | disclosed |
| EP-1864274-A2 | ILLUMINATING DEVICE COMBINING A LED AND A DIFFUSING SHEET | ARKEMA FRANCE (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100126-A2 | ILLUMINATING DEVICE COMBINING A LED AND A DIFFUSING SHEET | ARKEMA FRANCE (FR) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006100127-A2 | ILLUMINATING DEVICE COMBINING A WHITE LED AND A DIFFUSING SHEET | ARKEMA FRANCE (FR) | 2006-09-28 | — | — | WO | disclosed |
| CN-1116333-C | Process for producing polycarbonate | BAYER AG (DE) | 2003-07-30 | — | — | CN | disclosed |
| CN-1412247-A | Flame-retarded synthetic resin composition | ASAHI DENKA KOGYO KK (JP) | 2003-04-23 | — | — | CN | disclosed |
| CN-1261903-A | Process for producing polycarbonate | BAYER AG (DE) | 2000-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | GRM2, GRM1, GRIN2C | ESR2 491/4885TRPA1 302/4885ESR1 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.