Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 3/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626880 | 0.87 | PSMB8 (0.59) | PSMB8PSMB5PIK3CGMAPTKDM4E | |
| SCHEMBL30010034 | 0.81 | MAPT (0.43) | PSMB8PSMB5MAPTKDM4EMEN1 | |
| SCHEMBL11639549 | 0.80 | MAPT (0.54) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL486127 | 0.80 | PIK3CG (0.58) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL11934535 | 0.78 | PIK3CG (0.56) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL17221435 | 0.78 | PIK3CG (0.56) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL16006862 | 0.78 | PIK3CG (0.56) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL17221714 | 0.78 | PIK3CG (0.61) | PSMB8PSMB5PIK3CGSOS1MAPT | |
| SCHEMBL687550 | 0.76 | MAPT (0.63) | PSMB8MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7899514 | 0.75 | LOXL2 (0.60) | PSMB8PSMB5PIK3CGSOS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458966-B1 | Dye intermediate and method | NYCOMED AMERSHAM PLC (GB) | 2002-10-01 | — | — | US | disclosed |
| EP-1002020-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | Nycomed Amersham plc (GB) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007793-A1 | DYE INTERMEDIATE AND METHOD TO MANUFACTURE DYES | NYCOMED AMERSHAM PLC (GB) | 1999-02-18 | — | — | WO | disclosed |