SCHEMBL7642912

SCHEMBL7642912

Nc1ccc[nH]c1=O.O=c1cccc[nH]1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 2/20 0.76
AURKB Q96GD4 2/20 0.76
INCENP Q9NQS7 2/20 0.76
FKBP5 Q13451 1/20 0.64
PARP1 P09874 4/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
JAK2 O60674 1/20 0.43
RPS6KA3 P51812 1/20 0.43
MELK Q14680 1/20 0.43
STK24 Q9Y6E0 1/20 0.43
DAO P14920 1/20 0.42
MAPT P10636 2/20 0.39
CASP1 P29466 2/20 0.39
THRB P10828 1/20 0.39
TTK P33981 1/20 0.39
MCL1 Q07820 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL87697 0.87
Hydrochloric Acid SCHEMBL4056092 0.85
SCHEMBL27324502 0.80 FKBP5 (1.00) AURKAAURKBINCENPFKBP5PARP1
SCHEMBL9596 0.80
Sulfamide SCHEMBL27834517 0.79 AURKA (0.83) AURKAAURKBINCENPFKBP5PARP1
Formamide SCHEMBL17503641 0.79 AURKA (0.83) AURKAAURKBINCENPFKBP5PARP1
SCHEMBL25414048 0.78
SCHEMBL1149107 0.78
SCHEMBL9813332 0.78
SCHEMBL8004964 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6379876-B1 FOR USE IN HERMOGRAPHY OR PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY 2002-04-30 US disclosed
EP-1164415-A2 Sheet comprising an ion exchanged reducing agent and methods of processing photographic elements in the presence of said sheet EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
EP-1164420-A2 Thermally processable imaging element comprising an ion exchanged reducing agent EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
EP-1164414-A1 Photographic element comprising a reducing agent bound to an ion exchange matrix EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
US-6316173-B1 SHEETS WITH BINDERS FOR PHOTOGRAPHY AND ION EXCHANGE MATRIX EASTMAN KODAK COMPANY 2001-11-13 US disclosed
US-6261757-B1 STORAGE STABILITY OF REDUCING AGENT EASTMAN KODAK COMPANY 2001-07-17 US disclosed
EP-0660175-B1 Control of replenishment during photographic development STERLING DIAGNOSTIC IMAGING (US) 2000-03-22 EP disclosed
US-5935771-A BRINGING DEVELOPER SOLUTION INTO CONTACT WITH A CYANIDE SCAVENGER EASTMAN KODAK COMPANY (US) 1999-08-10 US disclosed
US-5935774-A RADIATION SENSITIVE COMPOSITE EASTMAN KODAK COMPANY (US) 1999-08-10 US disclosed
US-5811226-A SCAVANGING THE RELEASED CYANIDE FROM PHOTOGRAPHIC DEVELOPER SOLUTION WITH PALLADIUM AND GOLD COMPOUNDS EASTMAN KODAK COMPANY (US) 1998-09-22 US disclosed
US-5541027-A Method for determining the proper replenishment for a developing solution E. I. DU PONT DE NEMOURS AND COMAPNY (US) 1996-07-30 US disclosed
EP-0346071-B1 Photographic process EASTMAN KODAK CO (US) 1996-03-13 EP disclosed
EP-0660175-A2 Control of replanishment during photographic development E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-28 EP disclosed
US-5238793-A Black and white film sensitized with cyanine dye is treated with solution containing triazine derivatives as solubilizers to prevent formation of solid dye particles in solution EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
EP-0346071-A2 Photographic process EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-12-13 EP disclosed
US-4387154-A SPACED MICROVESSELS HAVING A SURFACE OPENING FILLED WITH PHOTOSENSITI MATERIAL; ANTIHALATION AGENTS; SUPPRESSION OF IMAGE SPREADING; X-RAY COLOR; BLACK AND WHITE FILMS EASTMAN KODAK COMPANY (US) 1983-06-07 US disclosed
US-4387146-A MICROVESSELS, PATTERNS EASTMAN KODAK COMPANY (US) 1983-06-07 US disclosed
US-4375507-A Imaging with nonplanar support multicolor filter elements EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
US-4362806-A PHOTOGRAPHY, SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1982-12-07 US disclosed
US-4228230-A Ultrasonic imaging of internally fogged silver halide elements EASTMAN KODAK COMPANY (US) 1980-10-14 US disclosed