SCHEMBL764323

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16475554	0.79	LMNA (0.39)	KDM4EALDH1A1POLBMAPTHPGD
	SCHEMBL28242793	0.73	KDM4E (0.59)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL29616919	0.73	KDM4E (0.61)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL18380643	0.73	KDM4E (0.61)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL471858	0.72	KDM4E (0.60)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL342910	0.72	KDM4E (0.59)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL8855987	0.70	KDM4E (0.58)	KDM4EALDH1A1MAPTHPGDLMNA
	Hydrochloric Acid SCHEMBL11553058	0.70	KDM4E (0.58)	KDM4EALDH1A1MAPTHPGDLMNA
	SCHEMBL471881	0.70	KDM4E (0.62)	KDM4EMAPTHPGDLMNANPC1
	SCHEMBL8855999	0.70	KDM4E (1.00)	KDM4EALDH1A1MAPTHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.