Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | FABP3 | P05413 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4189216 | 1.00 | CES2 (0.50) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL3908469 | 0.90 | — | — | |
| SCHEMBL6158213 | 0.90 | — | — | |
| SCHEMBL3175905 | 0.82 | CES1 (0.46) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL3175895 | 0.82 | CES1 (0.46) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL9353035 | 0.78 | — | — | |
| SCHEMBL17221046 | 0.78 | CES1 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL17221049 | 0.78 | CES1 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL17221050 | 0.78 | CES1 (0.48) | CES2CES1GPR84PPARGPPARD | |
| SCHEMBL23048256 | 0.76 | EP300 (0.47) | CES1PPARGPPARDPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916640-B1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-06-12 | — | — | EP | claimed |
| US-6288011-B1 | AGRICULTURE, EFFICIENCY | AMERICAN CYANAMID CO. | 2001-09-11 | — | — | US | claimed |
| US-6207846-B1 | REACTING 3-ARYL-1,1,2-TRIFLUORO-1-PROPENE WITH A REDUCING AGENT; THEN A LITHIUM BASE; THEN ARYLCHLOROSILANE COMPOUND | AMERICAN CYANAMID CO. | 2001-03-27 | — | — | US | claimed |
| US-6159956-A | Process and intermediate compounds for the preparation of difluorovinylsilane insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 2000-12-12 | — | — | US | claimed |
| EP-0916640-A1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | claimed |
| EP-0916640-B1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | BASF AG (DE) | 2002-06-12 | — | — | EP | disclosed |
| US-6288011-B1 | AGRICULTURE, EFFICIENCY | AMERICAN CYANAMID CO. | 2001-09-11 | — | — | US | disclosed |
| US-6235754-B1 | USING 1,4-DIARYL-(2-FLUORO- OR 2,3-DIFLUORO-)-2-BUTENE | AMERICAN CYANAMID COMPANY | 2001-05-22 | — | — | US | disclosed |
| US-6207846-B1 | REACTING 3-ARYL-1,1,2-TRIFLUORO-1-PROPENE WITH A REDUCING AGENT; THEN A LITHIUM BASE; THEN ARYLCHLOROSILANE COMPOUND | AMERICAN CYANAMID CO. | 2001-03-27 | — | — | US | disclosed |
| US-6159956-A | Process and intermediate compounds for the preparation of difluorovinylsilane insecticidal and acaricidal agents | AMERICAN CYANAMID CO. (US) | 2000-12-12 | — | — | US | disclosed |
| EP-0933027-A1 | Methods and compositions for protecting animals and humans against attack and infestation by arthropod and helminth parasites | American Cyanamid Company (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0916640-A1 | 1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents | American Cyanamid Company (US) | 1999-05-19 | — | — | EP | disclosed |