SCHEMBL764361

SCHEMBL764361

CC1NC(=O)C(C)NC1=O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.58
BRPF1 P55201 1/20 0.44
CREBBP Q92793 1/20 0.44
GSK3B P49841 1/20 0.35
CRBN Q96SW2 1/20 0.32
POLB P06746 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16350668 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL13424753 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL14005348 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL16316014 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL12809719 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL16316012 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL13074412 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL1226598 1.00 TSHR (0.58) TSHRBRPF1CREBBPGSK3BCRBN
SCHEMBL14612064 0.92
SCHEMBL4404117 0.79 TSHR (0.41) TSHRBRPF1CREBBPHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4369947-B1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2026-04-01 EP claimed
US-20240324641-A1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2024-10-03 US claimed
EP-4369947-A1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR Givaudan SA (CH) 2024-05-22 EP claimed
CN-115536598-B New synthesis method of 1, 4-dimethyl-2, 5-piperazine dione compound 青岛科技大学 2024-04-02 CN claimed
CN-117729856-A Flavor enhancer for providing flavor to roast chicken 奇华顿股份有限公司 2024-03-19 CN claimed
WO-2023285674-A1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2023-01-19 WO claimed
CN-115536598-A Novel synthesis method of 1,4-dimethyl-2,5-piperazinedione compound 青岛科技大学 2022-12-30 CN claimed
EP-2594134-B1 USE OF AN AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (MANAGEMENT: RURAL DEV ADMINISTRATION) (KR) 2017-08-02 EP claimed
CN-105367505-A Novel synthetic method of 3,6-dimethly-2,5-dioxopiperazine SULI PHARMACEUTICAL TECH JIANGYIN CO LTD 2016-03-02 CN claimed
CN-103118540-B Pesticide containing 2, 5-diketopiperazine derivative as active ingredient Rural Development Office (KR) 2016-02-17 CN claimed
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Kongju National University Industry- University Cooperation Foundation (KR) 2013-07-25 US claimed
EP-2594134-A2 AGRICULTURAL CHEMICAL CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT Republic of Korea (Management: Rural Development Administration) (KR) 2013-05-22 EP claimed
EP-0425344-B1 Light polarizing materials and suspensions thereof RESEARCH FRONTIERS INC (US) 1994-05-18 EP claimed
US-5130057-A Light polarizing materials and suspensions thereof RESEARCH FRONTIERS INCORPORATED (US) 1992-07-14 US claimed
EP-0425344-A2 Light polarizing materials and suspensions thereof RESEARCH FRONTIERS INCORPORATED (US) 1991-05-02 EP claimed
JP-3167290-A None JP disclosed
EP-4369947-B1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2026-04-01 EP disclosed
US-4808739-A HYDRAULIC FRACTURING FLUIDS, SUBTERRANEAN PLUGGING IN OIL AND GAS WELLS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-28 US disclosed
EP-0282253-A2 Cross-linking titanium & zirconium chelates & their use E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-14 EP disclosed
US-4006261-A Flavoring with mixtures of theobromine and cyclic dipeptides FIRMENICH S.A. (CH) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190177-A1 AGRICULTURAL AGENT CONTAINING 2,5-DIKETOPIPERAZINE DERIVATIVE AS ACTIVE INGREDIENT HDHD5, DAZAP1, MAPKAPK5 TSHR 4262/4885BRPF1 1029/4885CREBBP 1307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.